TCRmodel Logo

TCRmodel

Automated high resolution modeling of T cell receptors

We offer a standalone version, available here, for predicting structures locally.

Enter TCR α sequence
Enter TCR β sequence
Enter peptide sequence
Enter MHC I sequence
or select gene from above

As an alternative to entering sequences, you can upload a FASTA file instead. Make sure to use the correct sequence order indicated here.

FASTA input

Click to view lists of class I and class II pMHC templates.

pMHC PDB templates to exclude:
pMHC PDB templates to include:
PDB templates date cutoff:

Example input: TCR / HLA-A*01 - SARS-CoV-2 ORF3 peptide complex   (reference)
Example output: TCR / HLA-A*01 - SARS-CoV-2 ORF3 peptide complex

Select TCR α sequence from gene

Select TCR β sequence from gene

Enter peptide sequence
Enter MHC I sequence
or select gene from above

Click to view lists of class I and class II pMHC templates.

pMHC PDB templates to exclude:
pMHC PDB templates to include:
PDB templates date cutoff:

Example input: TCR / HLA-A*01 - SARS-CoV-2 ORF3 peptide complex   (reference)
Example output: TCR / HLA-A*01 - SARS-CoV-2 ORF3 peptide complex

Enter TCR α sequence
Enter TCR β sequence
Enter peptide sequence
Enter MHC II α sequence
or select gene from above
Enter MHC II β sequence
or select gene from above

As an alternative to entering sequences, you can upload a FASTA file instead. Make sure to use the correct sequence order indicated here.

Example fasta input

Click to view lists of class I and class II pMHC templates.

pMHC PDB templates to exclude:
pMHC PDB templates to include:
PDB templates date cutoff:

Example input: 4285 TCR - R175H neoantigen peptide complex   (reference)
Example output: 4285 TCR - R175H neoantigen peptide complex

Select TCR α sequence from gene

Select TCR β sequence from gene

Enter peptide sequence
Enter MHC II α sequence
or select gene from above
Enter MHC II β sequence
or select gene from above

Click to view lists of class I and class II pMHC templates.

pMHC PDB templates to exclude:
pMHC PDB templates to include:
PDB templates date cutoff:

Example input: 4285 TCR - R175H neoantigen peptide complex   (reference)
Example output: 4285 TCR - R175H neoantigen peptide complex