TCR-pMHC complex modeling Unbound TCR modeling Enter sequence Select from gene Enter TCR α sequence Enter TCR β sequence Enter peptide sequence Select MHC gene Class I Class II Species Human Enter sequence Advanced options Refine CDR3 loops PDB templates to exclude: Example input: A6 TCR / HLA-A*02 - TAX Peptide complex (reference) Example output: A6 TCR - HLA-A*02/TAX peptide Species Human Enter sequence Advanced options Refine CDR3 loops PDB templates to exclude: Example input: SP3.4 TCR - DQ8/gliadin peptide (reference) Example output: SP3.4 TCR - DQ8/gliadin peptide TCR α chain. Select sequence from gene: Species Human Mouse Generate sequence TCR β chain. Select sequence from gene: Species Human Mouse Generate sequence Enter peptide sequence Select MHC gene Class I Class II Species Human Enter sequence Advanced options Refine CDR3 loops PDB templates to exclude: Example input: A6 TCR / HLA-A*02 - TAX Peptide complex (reference) Example output: A6 TCR - HLA-A*02/TAX peptide Species Human Enter sequence Advanced options Refine CDR3 loops PDB templates to exclude: Example input: SP3.4 TCR - DQ8/gliadin peptide (reference) Example output: SP3.4 TCR - DQ8/gliadin peptide Enter TCR sequence Select from Germline gene Batch submission Paste your sequence TCR α chain Paste your sequence TCR β chain Advanced options Refine CDR3 loops PDB templates to exclude: Example input: 3995 KRAS_G12D TCR (reference) Example output: 3995 KRAS_G12D TCR Select TCR α sequence from gene Species Human Mouse Generate sequence Select TCR β sequence from gene Species Human Mouse Generate sequence Advanced options Refine CDR3 loops PDB templates to exclude: Example input: F26 Flu_M1 TCR (reference) Example output: F26 Flu_M1 TCR TCR α chain: Upload TCR α chain sequences: TCR β chain: Upload TCR β chain sequences: Advanced options Refine CDR3 loops PDB templates to exclude: Example input: TCRα.fasta TCRβ.fasta (reference) Example output: TCRM18G_190312_101922
